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MC Divice
MC Divice
MC Divice
Sample Processor Flow Cell and Sensor Component
The MC Device detects and analyzes tensile force and/or the rigidity change of thin-layered protein MC film by a highly sensitive force sensor. The MC film is fabricated by the electrospray deposition method, and becomes a freestanding film by treatment with cross-linking agents. The film is perforated and retained by a pair of tungsten pins within a micro-cell and in contact with various kinds of solutions. One end of the pin is a force sensor to detect tensional change larger than 0.1µN, and the other end of the pin is connected to piezo-oscillator to measure the film rigidity by providing micro-vibrations.
Description of the MC
Outline of MC divice
Component Parts
The instrument is made up of the measuring assembly, the sample supply assembly, the motor assembly, the dry air supply assembly, and the PC unit for controlling and/or measuring.
Description
As well as being equipped with a highly sensitive force sensor, the measuring assembly has a mechanism to perforate the film and to move it to a measurement cell. The sample supply assembly can incorporate 50 types of small volume samples (up to 2ml) and 3 types of large volume samples (up to the size of the container), and can supply the samples to the cell either manually or automatically. The whole procedure is controlled by the computer system attached to the equipment, and the data is processed and analyzed immediately by the computer.
Product Specifications
Components Specifications
Measuring assembly force sensor, micro-cell, monitoring video camera, mechanism to perforate and to move the film
Sample supply assembly Holding 50 small volume vials and 3 large volume bottles
Personal Computer Windows XP, control software, analytical software
Power source AC100V
Accessories Motor assembly, dry air supply assembly, monitor, keyboard, mouse
Advantage of the MC Technology
MC allows :
  • sensitive detection of protein conformational change in real-time, without the use of labels
  • sensitive detection of molecular interaction that induces protein conformational change
  • sensitive detection independent of the mass of ligands
  • kinetic analysis and quantitative analysis
  • evaluation of material properties such as nano-fibers
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